HoLEP is particularly advantageous because it provides enucleation with complete tissue removal and is able to treat very large glands.

• A. HoLEP is not recommended for large prostates
• B. HoLEP offers only partial tissue removal
• C. HoLEP provides enucleation with complete tissue removal and is suitable for very large glands
• D. HoLEP requires conversion to open surgery in most cases

Answer: (C)

Enucleation with complete tissue removal and the ability to treat very large glands is what HoLEP excels at. The technique uses a holmium laser to separate the enlarged prostate tissue (the adenoma) cleanly from the surrounding capsule along the natural surgical plane. This allows nearly all of the obstructive tissue to be removed in one piece, and then the tissue is morcellated and extracted. Because the removal is tissue-complete and not limited by gland size, HoLEP is particularly effective for very large prostates, where traditional TURP becomes impractical due to longer operative times and increased bleeding risk. In experienced hands, you don’t usually have to convert to open surgery to finish the job, which is another advantage over some older approaches. The statement that HoLEP provides enucleation with complete tissue removal and is suitable for very large glands is therefore the best description of its benefit.