Syphilis, if left untreated, can spread from the initial ulcer to which system causing death years later?

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Multiple Choice

Syphilis, if left untreated, can spread from the initial ulcer to which system causing death years later?

Explanation:
Untreated syphilis progresses to late-stage involvement of the nervous system. The bacteria can invade the central nervous system, causing neurosyphilis, which in its various forms (such as general paresis or tabes dorsalis) disrupts brain and spinal cord function. Over years, this CNS damage can lead to severe neurological decline and death. Other organ systems can be affected as well, but the late fatal complication most directly linked to the initial infection is nervous system involvement.

Untreated syphilis progresses to late-stage involvement of the nervous system. The bacteria can invade the central nervous system, causing neurosyphilis, which in its various forms (such as general paresis or tabes dorsalis) disrupts brain and spinal cord function. Over years, this CNS damage can lead to severe neurological decline and death. Other organ systems can be affected as well, but the late fatal complication most directly linked to the initial infection is nervous system involvement.

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