Which tumor marker is commonly associated with seminoma and used in follow-up?

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Multiple Choice

Which tumor marker is commonly associated with seminoma and used in follow-up?

Explanation:
Seminomas can contain syncytiotrophoblastic cells that produce human chorionic gonadotropin, so measuring hCG in the blood is used to monitor these tumors. Elevated hCG before treatment can indicate seminoma with those cells, and during follow-up rising levels can signal relapse while falling levels indicate a good response to therapy. AFP, by contrast, is more associated with nonseminomatous tumors like yolk sac tumors; CA-125 is an ovarian cancer marker, and CEA is linked to colorectal and some other cancers. Thus, hCG is the marker commonly linked to seminoma and used in follow-up.

Seminomas can contain syncytiotrophoblastic cells that produce human chorionic gonadotropin, so measuring hCG in the blood is used to monitor these tumors. Elevated hCG before treatment can indicate seminoma with those cells, and during follow-up rising levels can signal relapse while falling levels indicate a good response to therapy. AFP, by contrast, is more associated with nonseminomatous tumors like yolk sac tumors; CA-125 is an ovarian cancer marker, and CEA is linked to colorectal and some other cancers. Thus, hCG is the marker commonly linked to seminoma and used in follow-up.

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